Postoperative Sleep Quality of Patients Sedation With i.v. Dexmedetomidine or Midazolam Undergoing TURP

China Medical University, China111 enrolled

Overview

The investigators designed a study to determine whether dexmedetomidine versus midazolam combined with spinal anesthesia would provide same postoperative sleep quality in patients undergoing transurethral prostatic resection.The bispectral index score (BIS) was monitored during the operation and the first postoperative night

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

111

Conditions

Sleep Quality of Patients Undergoing TURP

Interventions

dexmedetomidineDRUG

The sedative solution administered intravenously started at rate of kg (weight of patient)\*0.6 ml/h over a 10-min period and then at rate of kg (weight of patient)\*0.15 ml/h through syringe pump to the end of surgery

MidazolamDRUG

Eligibility

Sex: MALEMin age: 60 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Participants were deemed eligible if they were candidates for spinal anesthesia undergoing TURP Exclusion Criteria: * The exclusion criteria were body mass index exceeding 30 kg/m2, preoperative Pittsburgh Sleep Quality Index global scores higher than 6, anesthesia time longer than 3 hours, allergy to drugs used in the study and treatment with sedatives and analgesics during the postoperative BIS-Vista monitoring period.

Locations (1)

the First Hospital of China Medical University

Shenyang, Liaoning, China

Outcomes

Primary Outcomes

The Change of postoperative sleep quality

The bispectral index score (BIS) was monitored during the operation and the first postoperative night

Time frame: preoperation, first postoperative night

Data from ClinicalTrials.gov

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