Phosphatidylcholine (LT-02) for Induction of Remission in Ulcerative Colitis

Inclusion Criteria: * Established diagnosis of ulcerative colitis * Active ulcerative colitis disease extent ≥ 15 cm * Active disease despite treatment with mesalamine Exclusion Criteria: * Crohn's disease, indeterminate colitis, ischemic colitis, radiation colitis, microscopic colitis, diverticular disease associated colitis, * Toxic megacolon or fulminant colitis * Colon resection * Evidence of infectious colitis * Celiac disease * Bleeding hemorrhoids * History or presence of ischemic heart disease, myocardial infarction, peripheral arterial disease, ischemic stroke, or transient ischemic attack * Any severe concomitant renal, endocrine, or psychiatric disorder * Any relevant known systemic disease * History of cancer in the last five years * Abnormal hepatic function or liver cirrhosis * Abnormal HbA1c at screening visit * Patients with known hypersensitivity to soy * Known intolerance/hypersensitivity to Investigational Medicinal Product (IMP) * Treatment with steroids/methotrexate/Tumor necrosis factor-alpha-antagonists/azathioprine/ 6-mercaptopurine/anti-integrin/coumarins * Treatment with other investigational drug * Existing or intended pregnancy or breast-feeding