Targeting the amount of fluid given to measurements of the patients own fluid status during major abdominal surgery has been linked with improved speed of recovery of gut function and reduced length of hospital stay, mortality and complications. Pleth variability index (PVI) offers a noninvasive, risk and pain free alternative to more invasive forms of monitoring to direct how much fluid to give. The study aims primarily to measure and compare how much fluid is given when guided by PVI compared to the established technique; oesophageal doppler during major abdominal surgery. The study will compare 40 patients undergoing major elective abdominal surgery. Patients will receive intraoperative fluid guided by either oesophageal doppler or PVI. Secondarily, the study will examine biochemical markers, length of hospital stay and how frequently complications occur
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
38
Fluid therapy guided by doppler
Fluid therapy guided by PVI
York Teaching Hospital
York, N Yorks, United Kingdom
Difference between fluid volumes administered in the intra-operative period
Time frame: End of operation
Difference in 24 hour fluid balance
Time frame: 24 hours
Post-operative morbiditiy survey
Time frame: 7 days
Biochemical Markers of Tissue Perfusion
Lactate and Base Excess
Time frame: 24 hours
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