The main objectives of this study are to test the hypotheses that: 1) consumption of beverages sweetened with sucrose will increase risk factors for cardiovascular disease to a greater extent than a naturally-sweetened fruit juice such as orange juice, and 2) chronic psychological stress may augment the adverse metabolic effects of sugar intake. The study intervention consists of 2-week's consumption of 25% of energy as sugar provided either as a sucrose-sweetened beverage or naturally-sweetened orange juice.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
23
intervention assigned: 2-week consumption of naturally-sweetened orange juice providing 25% of energy requirement
intervention assigned: 2-week consumption of sucrose-sweetened beverage providing 25% of energy requirement
Clinical Research Center
Sacramento, California, United States
24-hour triglyceride area under the curve
28 serial blood samples are collected over a 24 hour period.
Time frame: Baseline and 2-week intervention
Markers of immune cell aging
Time frame: Baseline and 2-week intervention
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