This study is designed to evaluate safety, pharmacokinetics and pharmacodynamics after single administration of KHK7580 for secondary hyperparathyroidism in patients receiving peritoneal dialysis.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
13
Oral administration
Kyowa Hakko Kirin
Tokyo, Japan
Number and types of adverse events
The safety of KHK7580 assessed by number and types of adverse events, laboratory tests, vital signs and electrocardiogram
Time frame: For 8 days
Profiles of pharmacokinetics
intact parathyroid hormone, whole parathyroid hormone, corrected serum calcium, phosphorus, intact fibroblast growth factor 23, ionized calcium, calcitonin
Time frame: Pre-dose, 0.5, 1, 2, 4, 8, 12, 24, 48, 72 and 168 hours post-dose
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