Long-Term Study of OnabotulinumtoxinA Treatment in Adult Patients With Upper Limb Spasticity

Inclusion Criteria: * For patients entering from the 191622-127 study, successful completion of study 191622-127 * For patients entering directly into study 191622-129, upper limb spasticity in the elbow and shoulder due to stroke, with the most recent stroke at least 3 months ago Exclusion Criteria: * Spasticity in the non-study upper limb that requires treatment * Presence of fixed contractures in of the study muscles in elbow or shoulder * Profound atrophy of muscles to be injected * Previous surgical intervention, nerve block, or muscle block for the treatment of spasticity in the study limb in the last 12 months * Injection of corticosteroids or anesthetics, use of casting or dynamic splinting or constraint-induced movement therapy (CIMT) for the study limb within 3 months * Ultrasound therapy, electrical stimulation, or acupuncture in the study limb within 1 month * Condition other than stroke contributing to upper limb spasticity * Diagnosis of myasthenia gravis, Eaton-Lambert syndrome, and/or amyotrophic lateral sclerosis