A Prospective Randomized Controlled Clinical Trial of Standard Versus Goal-Directed Perioperative Fluid Management (GDT) for Patients Undergoing Radical Cystectomy

Inclusion Criteria: * Adults (21 years old or greater) who are able to provide informed consent * Patients who undergo an open, elective radical cystectomy Exclusion Criteria: * Patients with active atrial fibrillation or flutter, since the algorithm is not accurate in case of cardiac arrhythmia * Female patients who are pregnant (female patients of child-bearing potential must have a negative serum pregnancy test ≤ 14 days prior to surgery or 15 to 30 days prior to surgery with a negative urine pregnancy test the morning of surgery) * Presence of ascites, because increased abdominal pressure interferes with EV1000 reading accuracy * BMI \> 45 or \<17, because increased abdominal pressure interferes with EV1000 reading accuracy