Topical Timolol Gel for the Treatment of Infantile Hemangiomas

Inclusion Criteria: * Written informed permission for study participation and the use of the patient's images are obtained from the patient's parent(s) or guardian(s), * The patient is between 7 days and 6 months of age at the time of enrollment, * and a proliferating HOI not requiring systemic therapy is present anywhere on the body, Multiple hemangiomas may be treated on same child, if the hemangioma meets this criteria. Exclusion Criteria: * patients who are not otherwise generally healthy; * at risk for imminent ulceration, life-threatening, function-threatening, or ulcerated; * patients who have previously received systemic, intra-lesional or topical corticosteroids, imiquimod, vincristine, alpha-interferon, propranolol or other beta blockers; * patients who have previously been treated for his/her HOI, including any surgical and/or medical procedures; * patients whose mothers have been breastfeeding the patient while also being treated with beta-blockers, systemic corticosteroids, vincristine or alpha-interferon; * patients who have previously experienced any anaphylactic reactions; patients with an unclear diagnosis of HOI; * patients participating in another clinical study or living in the same household as an infant already participating in this study; * patients born prematurely who have not yet reached his/her term equivalent age; and patients with parent(s) or guardian(s) who cannot be contacted by telephone in case of emergency.