Prospective Database of Gastrointestinal Stromal Cell Tumors (GISTs)

Washington University School of Medicine187 enrolled

Overview

Specific Aim 1: To determine patient compliance with a GIST surveillance program Hypothesis: Patient compliance with a GIST surveillance program will be low. Specific Aim 2: To determine if EUS features of GIST, particularly maximum size, change significantly during a surveillance program. Hypothesis: EUS features of GIST, particularly maximum size, will not change significantly during a surveillance program. Specific Aim 3: To determine if EGD measures of GIST size correlate well with EUS measures of GIST size. Hypothesis: EGD measures of GIST size will correlate well with EUS measured of GIST size.

Study Type

OBSERVATIONAL

Enrollment

187

Conditions

Gastrointestinal Stromal Cell Tumors Foregut Subepithelial Lesions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * presenting for EUS with an indication for a SEL in the stomach or esophagus * at least 18 years of age * able to provide informed consent Exclusion Criteria: * no subepithelial lesion in the stomach or esophagus' * less than 18 years of age * unable to provide informed consent

Locations (1)

Outcomes

Primary Outcomes

Determine the natural history of small (< 30 mm) SELs discovered evaluated by EUS.

Time frame: 3 years

Secondary Outcomes

Determine the degree of patient compliance with surveillance recommendations.

Time frame: 3 years

Describe the diagnostic yield of EUS±FNA in evaluating SELs.

Time frame: 2 weeks

Compare SEL size estimation based on EUS, EGD and computer tomography (CT).

Time frame: 1 day