Monitoring Hypertensive Patients's Cerebral Oxygen Saturation

Huazhong University of Science and Technology41 enrolled

Overview

The purpose of this study is to determine whether there is a significant decrease in cerebral oxygen saturation in hypertensive patients undergoing major abdominal surgery and their correlation with standard monitoring parameters.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Surgical Complications From General Anesthesia Hypertension Cerebral Ischemia Cerebral Anoxia

Eligibility

Sex: ALLMin age: 30 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients have hypertension more than 3 year,whether well-controlled or uncontrolled, * scheduled for major abdominal surgery for at least 2 h * under general anesthesia * American Society of Anesthesiologists（ASA）physical status : II \~ III * Age \> 30 Exclusion Criteria: * pre-existing cerebral pathology for example episodes of cerebral ischemia or stroke; * ASA physical status \>IV * hepatic failure * renal failure * preoperative Mini-Mental State Examination (MMSE) score less than 24 * a history of cardiovascular surgery or craniotomy * cardiac failure * respiratory failure

Locations (1)

Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

Outcomes

Primary Outcomes

decreases in cerebral oxygen saturation (rSO2) during the surgery

Time frame: every 5 minutes throughout the surgery

Secondary Outcomes

Change from baseline in Mini-Mental State Exam (MMSE) perioperative period

Time frame: Baseline, 4 day after surgery

Data from ClinicalTrials.gov

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