Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation

Inclusion Criteria: * Male or female ages aged ≥21 and ≤75 years * Genotyped positive for a FTD-GRN mutation, and aware of it * Prodromal to moderate FTD-GRN * Resides in a stable living situation, living at home, senior residential setting, or an institutional setting without the need for continuous (ie, 24-hour) nursing care * Proficiency (oral and written) in the language in which study-related documents, including the ICF and standardized tests, will be administered * Able to swallow capsules * Be in good general health, willing and able to comply with the protocol requirements, and expected to complete the study as designed (in the judgment of the investigator) Exclusion Criteria: * Clinically significant abnormalities on physical examination, medical history, ECG, vital signs, laboratory values, or unstable medical or psychiatric illness * Females who are pregnant, breastfeeding, or planning to become pregnant during the study