The purpose of the study is to determine if the administration of a mix of Sufentanil and Morphine in intrathecal is a better analgesia regimen than PCA alone in patient post-VATS.
This study will compare the need for analgesia (Hydromorphone PCA) of two groups of patients post-VATS. The placebo group will only have a PCA for post-operative analgesia, witch is the standard care for patient post-VATS. The experimental group will have a intrathecal injection of a mix of morphine and sufentanil before the induction of anesthesia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
34
Centre hospitalier universitaire de Sherbrooke
Sherbrooke, Quebec, Canada
Hydromorphone consommation
The amount of Hydromorphone needed by the patient in the first 24hr after his VATS.
Time frame: 24hr
Pain
A VAS will be used.
Time frame: Every 4h x 24hr
Adverse effects of narcotics
Including : * Saturation \[Saturation (%) and the need for oxygen (l/min) will be assess to evaluate the incidence of desaturation and hypoventilation in both arms\] * Sedation \[Sedation will be evaluate with the Riker Sedation Agitation Scale\] * Respiratory rate \[To evaluate the incidence of hypoventilation (\<8/min) and to compare the average between both arms\]
Time frame: Every 4h x 24hr
Adverse reactions associate with rachianesthesia
Including : * Backache * Headache * Legs strength
Time frame: 24hr
Adverse reactions of narcotics
Including : * Nausea * Pruritis * Urinary retention
Time frame: 24hr
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