For the chemical lupeol isolated from eggplant, we applied it to one side of face, and applied vehicle control to another side for 8 -weeks. The study was performed in a 8-week, randomized controlled, split face fashion. Investigators evaluated safety and efficacy during baseline, 2 weeks, 4weeks, and 8 weeks after beginning of study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
25
Patients are supposed to apply lupeol cream to one side of their face two times per day for 8 weeks.
Patients are supposed to apply their control vehicle to the other side of their face for 8 weeks
Seoul National University Hospital
Seoul, Seoul, South Korea
Acne lesion counts as a measure of efficacy
Both inflammatory \& non-inflammatory acne lesions of both of their facial sides
Time frame: 8 weeks after beginning of applications
Number of Participants with Adverse Events as a Measure of Safety and Tolerability
Among total patients enrolled in this study, number of patients either experiencing objective adverse events or subjective uncomfortableness were counted
Time frame: 8 weeks after beggning of applications
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