Oxytocin and Emotion Processing

University Hospital, Bonn97 enrolled

Overview

The purpose of this study is to determine whether oxytocin influences emotional processing and learning of emotional and social stimuli.

An effect of OXT on emotion processing and anxiety has been broadly investigated in animal studies. However, in humans, effects seem more complex. The rationale of the study is to examine direct effects of OXT to processing and learning of emotional and social values in humans.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Healthy Males

Interventions

OxytocinDRUG

Eligibility

Sex: MALEMin age: 20 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy male volunteers Exclusion Criteria: * Current or past psychiatric disease * Current or past physical illness * Psychoactive medication * Tobacco smokers * MRI contraindication

Outcomes

Primary Outcomes

Brain activity

fMRI

Time frame: During emotion processing

Secondary Outcomes

Psychophysiological response

Skin conductance response

Time frame: During stimuli presentation

Data from ClinicalTrials.gov

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