Endobronchial Ultrasound-transbronchial Needle Aspiration (EBUS-TBNA) Sample Division

University Hospital, Essen88 enrolled

Overview

EBUS-TBNA specimen are used for lung cancer diagnosing and staging, as well for molecular analysis. The purpose of this study is to evaluate if samples from on lymph node site can be divided for diagnosis and molecular analysis.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Lung Cancer

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * clinical diagnosis of lung cancer * enlarged mediastinal or hilar lymph nodes (\>10 mm) Exclusion Criteria: \-

Locations (1)

Ruhrlandklinik-UK Essen

Essen, Germany

Outcomes

Primary Outcomes

Sensitivity and Specificity of lung cancer diagnosis

We aim to evaluate if splitting the obtained specimen will have an impact on lung cancer diagnosis performed by histopathologic analysis

Time frame: 6 month

Secondary Outcomes

Percentage of successful performed molecular RNA based analysis

We will analyse the second half of the sample regarding molecular analysis. RNA concentration and RNA integrity score will be assessed before a new RNA based test will be evaluated.

Time frame: 3 month

Data from ClinicalTrials.gov

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