The folliculitis decalvans (FD) is an orphan disease , common in consultation specialized on scalp. This disease is currently not curable, responsible for significant for patients. The pathophysiology is poorly understood, Staphylococcus aureus (SA) appears to play a role, never previously studied, and the study will attempt to clarify it. Controversies in the literature on the pathophysiological hypotheses can be summed up as follows : FD is it an infectious folliculitis where SA (almost always found on the lesions plays a direct role possibly aided by a lack of local immune protection , or is it a pustular inflammatory unknown cause where the SA has no direct role but is a cofactor or a simple germ superinfection. Our study has plans to bring new evidence to help decide between these two opposite but not mutually exclusive concepts .
Study Type
OBSERVATIONAL
Enrollment
40
Saint-Louis Hospital
Paris, Paris, France
presence of Staphylococcus Aureus in cutaneous biopsies (at least one colony)
The primary endpoint is the presence of Staphylococcus Aureus in cutaneous biopsies before any therapy and notably antibiotics.
Time frame: 1 day
presence of Staphylococcus Aureus in cutaneous biopsies (at least one colony) after treatment
Time frame: 10 weeks
presence of Staphylococcus Aureus in nasal swab (at least one colony)
Time frame: 1 day
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.