To notify the effect of aspiration of excessive endometrial fluid in addition to Diosmin in cases undergoing intracytoplasmic sperm injection (ICSI) cycles.
Objectives: To notify the effect of aspiration of excessive endometrial fluid in addition to Diosmin in cases undergoing intracytoplasmic sperm injection (ICSI) cycles. Study design: Prospective randomized controlled clinical trial. Patients and Methods: 200 women with excessive endometrial fluid by transvaginal ultrasound during ICSI cycles are randomly scheduled into two equal groups. In group A, one tab every 8 hs Diosmin ( 500mg) beginning from the day of ovum retrieval in addition to aspiration of the fluid by an IUI catheter ; while in group B (control group), no thing is given or done. The main outcome measures are presence of the fluid on the day of embryo transfer and the pregnancy rate on those patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
200
one tab every 8 hs Diosmin ( 500mg) beginning from the day of ovum retrieval in addition to aspiration of the fluid by an IUI catheter
Benha univesity hospital
Banhā, El Qualyobia, Egypt
the pregnancy rate
is assessed by :serum hCG test Beta sub-unit of hCG (serum hCG test)
Time frame: is checked 16 days after embryos transfer
presence of the fluid on the day of embryo transfer
detection of excessive endometrial fluid by transvaginal ultrasound during ICSI cycles
Time frame: at the day of embryo transfer
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