The aim of this study is to describe, in a real-life context, the impact of an epoetin alpha biosimilar, Retacrit®, on anaemia in patients receiving chemotherapy, according to concomitant iron supplementation.
This is a longitudinal, observational, prospective, multicentre, cohort study, conducted on a representative sample of public and/or private hospital-based oncologists and haematologists practicing in Metropolitan France.
Study Type
OBSERVATIONAL
Enrollment
2,167
Impact of an epoetin alpha biosimilar with or without iron supplementation on chemotherapy-induced anemia
The efficiency of epoetin alpha biosimilar will be assessed by the responders'rate according to European Society for Medical Oncology (ESMO) guidelines. This rate will be compared depending on the iron supplementation. The safety will be assessed by the record of adverse effects (serious or not) and treatment discontinuation.
Time frame: Patients are included at the time of the epoetin alpha biosimilar treatment initiation for chemotherapy-induced anemia and followed up to 12 to 16 weeks
Characteristics of patients receiving treatment with an epoetin alpha biosimilar, Retacrit®, for chemotherapy induced anaemia
Time frame: Baseline visit
Procedures for evaluating possible iron deficiency and iron supplementation
Time frame: At 12 to 16 weeks from baseline or at the end of chemotherapy
Impact of iron supplementation on the doses of Retacrit® used, and on treatment duration
Time frame: At 12 to 16 weeks from baseline or at the end of chemotherapy
Experience of patients treated with Retacrit®
Time frame: At 12 to 16 weeks from baseline or at the end of chemotherapy
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Hopital Louis Pasteur
Colmar, Alsace, France
CH Emile Muller
Mulhouse, Alsace, France
CAC Paul Strauss
Strasbourg, Alsace, France
Chu Hopital Civil
Strasbourg, Alsace, France
MEDIPOLE
Aix-les-Bains, Auvergne-Rhône-Alpes, France
CHRA
Annecy, Auvergne-Rhône-Alpes, France
Clinique CONVERT
Bourg-en-Bresse, Auvergne-Rhône-Alpes, France
Ch Chambery
Chambéry, Auvergne-Rhône-Alpes, France
Chu Grenoble
Grenoble, Auvergne-Rhône-Alpes, France
Ch Valence
Valence, Auvergne-Rhône-Alpes, France
...and 59 more locations