Clinical Trial of Autologous Adipose Tissue-Derived Mesenchymal Progenitor Cells (MPCs) Therapy for Knee Osteoarthritis

Inclusion Criteria: 1. The subject is between 18-70 years of age, regardless of gender 2. The subject has a Kellgren-Lawrence grading, as determined by American College of Rheumatology (ACR) criteria for osteoarthritis of the knee, below grade 4 3. The subject or the subject's legally acceptable representative must be willing to participate in the trial, to receive cell therapy and to provide signed and dated informed consent forms Exclusion Criteria: 1. The subject has an allergic history or is of an allergic constitution 2. The subject has uncontrolled or hard-to-control diseases of heart, liver, kidney or lung 3. The subject has uncontrolled or hard-to-control diseases of cardiovascular or endocrine system 4. The subject has severe infectious diseases or a malignant tumour 5. The subject has coagulation disorders 6. The subject has a BMI of over 30 7. The subject has used traditional Chinese medicine containing anti-inflammatory agents in the 2 weeks preceding the trial 8. The subject has received other intra-articular injections in the 2 months preceding the trial 9. The subject has complications or diseases of: systemic or rheumatoid arthritis, Chondrocalcinosis articular， Hemochromatosis，inflammatory arthropathy，avascular necrosis of femoral head，Paget's disease，hemophilic arthropathy，infectional arthritis，Charcot's disease，villonodular synovitis or synovial chondromatosis 10. The subject tests positive for: HIV, hepatitis virus, syphilis or other infectious diseases 11. The subject has a history of alcoholism, drug abuse, or mental illness 12. The subject has participated in any other clinical trial in the 3 months prior to this trial 13. The subject is pregnant, lactating or is planning to conceive within the next 6 months 14. The subject has any other unsuitable or adverse condition to be determined by the investigator