Effects of Yoga on Bone Metabolism in Premenopausal Women

University of Oklahoma47 enrolled

Overview

This study examined the effects of 8 months of Yoga training on bone density and bone turnover markers in premenopausal women, ages 35-50 years. The style of Yoga used was power Yoga that involved postures with a jumping component. The investigators hypothesized that the Yoga intervention would result in beneficial improvements in bone turnover markers, by increasing the bone formation marker and decreasing the bone resorption marker.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Bone Health Osteoporosis

Interventions

Yoga GroupOTHER

8 months of Yoga training

Eligibility

Sex: FEMALEMin age: 35 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * participants had not been engaged in resistance training or in Yoga exercise for at least 12 months prior to the study * did not have chronic back or joint problems or cardiovascular disease * not taking antihypertensive drugs or any medication that affects bone density * not taking hormonal contraception * they self-reported having regular menstrual cycles. Exclusion Criteria: * body weight more than 300 pounds

Locations (1)

Department of Health and Exercise Science, University of Oklahoma

Norman, Oklahoma, United States

Outcomes

Primary Outcomes

Change in bone mineral density from baseline to 8 months

Time frame: pre and post 8 months training

change in bone turnover markers

Time frame: pre and post 8 month intervention

change in tibia bone characteristics

changes in volumetric bone mineral density and bone strength of the non-dominant tibia assessed by peripheral Quantitative Computed Tomography (pQCT)

Time frame: pre and post 8 month intervention

Changes in muscular strength

Isotonic 1 repetition maximum (1RM) for 4 lower body and 2 upper body resistance exercises

Time frame: pre and post 9 month intervention

Change in arterial compliance

Arterial compliance of the large and small arteries was assessed using Pulse Contour analysis.

Time frame: pre and post 8 month interventon

Change in Insulin-like Growth Factor-1 (IGF-I) and Insulin-like Growth Factor BP3 (IGFBP3)

Time frame: pre and post 8 month intervention

Secondary Outcomes

Daily Calcium intake

Calcium intake is a potential confounding variable. Participants were encouraged to increase their calcium intakes if found to be low before the intervention began.

Time frame: pre and post 8 month intervention

Menstrual History

This information was used to monitor menstrual characteristics to ensure they were still premenopausal at the post test.

Data from ClinicalTrials.gov

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