This study will evaluate the safety and efficacy of human central nervous system stem cell transplantation into patients with traumatic injury in the cervical region of the spinal cord.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
31
surgery arm
Rancho Los Amigos National Rehabilitation Center/USC
Downey, California, United States
University of Miami Miller School of Medicine
Miami, Florida, United States
Change from baseline in ISNCSCI upper extremity motor scores
Time frame: Up to one year after enrollment
Number of participants with serious and non-serious adverse events
Safety measures will include collection of adverse events, laboratory tests, neurological examination, ISNCSCI motor and sensory scores, pain and allodynia assessment, AIS grade, physical examination and modified Ashworth scale
Time frame: Up to one year from the time of enrollment
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Northwestern University
Chicago, Illinois, United States
University of Maryland Medical Systems
Baltimore, Maryland, United States
University of Michigan Health System
Ann Arbor, Michigan, United States
University of Minnesota/Courage Kenny Rehabilitation Institute
Minneapolis, Minnesota, United States
Mount Sinai Medical Center, Dept of Neurosurgery
New York, New York, United States
Thomas Jefferson University
Philadelphia, Pennsylvania, United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States
University of Texas, Mischer Neuroscience Institute
Houston, Texas, United States
...and 4 more locations