Efficacy and Security of an Endovascular Treatment as First Choice Procedure Compared With a Standard Intravenous Thrombolytic Therapy Treatment for Patients With Acute Ischemic Stroke Within 4.5 Hours After Onset

Inclusion Criteria: * 80 or less years old patients with acute stroke produced by a main artery occlusion * NIHSS National Institutes of Health Stroke Scale score greater than 6 (severe neurological impairment) * Patients receiving EVT or IVT within 4.5 hours after onset Exclusion Criteria: * EVT or IVT contraindication * Previous neurological impairment, severe concomitant disease or poor prognosis. * Pregnancy or breastfeeding * Known hypersensitivity to any study drugs * Severe organic disease for which there is not risk compensation.