A Single Center Study to Evaluate the Penetration of RO7033877 Into the Lung in Healthy Volunteers

Inclusion Criteria: * Male or female healthy volunteers, 18 to 55 years of age, inclusive. A female participant is eligible to participate if she is of non-childbearing potential defined as postmenopausal or surgically sterile * Healthy status is defined by absence of evidence of any active or chronic disease following a detailed medical and surgical history, a complete physical examination including vital signs, 12-lead electrocardiogram (ECG), hematology, blood chemistry, serology and urinalysis * Body mass index (BMI) between 18 and 30 kg/m2 inclusive * Nonsmokers * Healthy male volunteers with female partners of childbearing potential must use adequate contraception methods Exclusion Criteria: * Evidence of active chronic disease * Regular consumption of drugs of abuse * Infection with human immunodeficiency virus (HIV), hepatitis B (HBV), or hepatitis C (HCV) * History of clinically significant hypersensitivity or allergic drug reactions * Clinically significant abnormalities (e.g. cardiovascular, laboratory values) * Abnormal blood pressure or vital signs * Contraindications to bronchoalveolar lavage (BAL)