More than half of patients with epilepsy achieve full control of their seizures with antiepileptic drugs (AEDs).The study is aimed to investigate effectiveness of an educational intervention in improving medication adherence in patients with epilepsy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE
Enrollment
280
A multifaceted intervention program was used to improve adherence and clinical outcomes in epileptic patients. However, this study mainly focused on behavioral treatment in the patients. Patient's intervention A three-week session will perform to improve medication adherence in patients in the intervention group. Face to face introductory motivational interviews (MI) will conduct to resolve patient ambivalence about change. Besides providingthe intervention for the patients, the health care team and the patient's family member will receive a brief intervention.All GPs and nurses as well as patients' family members participate in a single session MI with the same procedure
All participants of the study in both group receive the Standard Care. Usually, patients in clinics receive a one-time session of brief advice to use medications regularly lasting approximately 5 minutes and deliver by nurse or physician. Some issues rise in this short session including coexisting diseases, the history of drug use, current disease and advice about the health risks of irregular medication use.
Qazvin University of Medical Sciences, Shahid Rajaei Hospital
Qazvin, Qazvin Province, Iran
changes in Patient-reported medication Adherence to antiepileptic drugs
The Medication Adherence Report Scale (MARS-5) will be used for assessing medication adherence to antiepileptic drugs
Time frame: changes from baseline , 3 Months and 6 months after the intervention
changes in serum levels of antiepileptic drugs
Serum anti-epileptic drug (AED) level monitoring will be collected to assess AED adherence or toxicity
Time frame: changes from baseline , 6 Months, 12 months and 18 months after the interventio
Changes in psychological predictors of medication adherence (intention, perceived behavioral control and Self-monitoring)
Time frame: Changes from baseline, 3 Months and 6 months after the intervention
Changes in action planning
The number of planning strategies is used by the patients before, at baseline, three months and six months after the intervention
Time frame: Changes from baseline, 3 Months and 6 months after the intervention
Changes in coping planning
Time frame: Changes from baseline, 3 Months and 6 months after the intervention
Changes in quality of life
Time frame: Changes from baseline, 3 Months and 6 months after the intervention
Changes in habit strength
Time frame: Changes from baseline, 3 Months and 6 months after the intervention
Changes in Seizure Severity
Time frame: Changes from baseline, 3 Months and 6 months after the intervention
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