The aim of this study is to evaluate the influence of presence of oral fungal infection, which leads to denture-related stomatitis, on blood pressure, endothelial function and immune cell phenotype in patients wearing dentures.
Study Type
OBSERVATIONAL
Enrollment
80
100 000 IU every 6 h as a suspension
Zbigniew Żak Voivodeship Dental Clinic
Krakow, Poland
RECRUITINGJagiellonian University Dental Clinic
Krakow, Poland
RECRUITINGChange from baseline in blood pressure
Ambulatory Blood Pressure Monitoring System
Time frame: Within 48h Prior to denture-related stomatitis treatment; 48h after recovery from denture-related stomatitis; 2 months after recovery from denture-related stomatitis
Change from baseline in endothelial function
Flow Mediated Dilatation
Time frame: Within 48h Prior to denture-related stomatitis treatment; 48h after recovery from denture-related stomatitis; 2 months after recovery from denture-related stomatitis
Changes in immune cell subset populations from baseline
Determination of cell subsets, activation markers and intracellular cytokine production
Time frame: Within 48h Prior to denture-related stomatitis treatment; 48h after recovery from denture-related stomatitis; 2 months after recovery from denture-related stomatitis
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