Cognitive remediation (CR) therapies refer to a number of recent developments to use behavioural strategies to improve neurocognitive abilities and improve everyday functioning in mental disorders such as schizophrenia, bipolar disorder, and depression. In this study, we aim to examine whether we can observe CR effects on measures of neuroplasticity, cognition, and functioning when using a rigorous control comparison group. We hypothesize that the active group will exhibit improvements in executive functioning composite scores, improved EEG theta-gamma frequency modulation, and increased EEG alpha power compared to the placebo group.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
Placebo version of executive function training
Queen's University
Kingston, Ontario, Canada
Change from baseline executive functioning composite score at post-treatment assessment
Composite score based on four tests of cognition
Time frame: Pre-training assessment (Week 1) and post-training assessment (Week 4)
Change from baseline EEG theta-gamma frequency modulation at post-treatment assessment
Predicted to improve in active CR (cognitive remediation) condition compared to placebo CR
Time frame: Pre-training assessment (Week 1) and post-training assessment (Week 4)
Change from baseline EEG alpha power at post-treatment assessment
Predicted to increase in active CR (cognitive remediation) condition compared to placebo CR
Time frame: Pre-training assessment (Week 1) and post-training assessment (Week 4)
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