Hypertrophic scar, a disfiguring tissue reaction to trauma, occurred in around 20 % of the population. The patients with hypertrophic scar usually seek medical assistance not just for the annoying appearance but mostly due to the intractable itchiness. There have been a variety of effective methods to alter the appearance of the scar. However, the treatments for itching from hypertrophic scar are scarce. In 2009, P.Gazerani used Botox to treat histamine-induced itch with favorable results. In the clinical setting, however, the efficacy of Botox to treat itch from hypertrophic scar was yet to be proven. Therefore, the goal of this study is to conduct a randomized controlled trials about using Botox to treat itch from hypertrophic scar.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
60
5U botulinum toxin in 1c.c. normal saline, local injection
1cc normal saline, local injection
Kaohsiung Veterans General Hospital
Kaohsiung City, Taiwan
RECRUITINGThe degree of itchiness
Time frame: 6 months
Pain scale
We'll ask the participant about the pain during injection. The question will be asked within one minute after drug injection.
Time frame: Within one minue after drug injection
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