Effect of Pharyngeal Inhibition by rTMS on Swallowing Function

University Hospital, Rouen10 enrolled

Overview

The aim of this study is to test the hypothesis that rTMS on the dominant swallowing hemisphere is able to modify swallowing coordination.

The aim of the study is to demonstrate that rTMS (on the dominant hemisphere, on the nondominant hemisphere and placebo rTMS) are able to modify swallowing coordination on healthy subjects. Swallowing function will be studied before and after rTMS with videomanometry.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Oropharyngeal Dysphagia

Interventions

magnetic stimulationPROCEDURE

rTMS on pharyngeal cortical area in healthy subjects or sham rTMS on pharyngeal cortical area in healthy subjects

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 18-50 years old * healthy subjects Exclusion Criteria: * epilepsia * brain injury * stroke * pregnancy

Locations (1)

VERIN

Rouen, France

Outcomes

Primary Outcomes

pharyngeal pressure

Swallowing function will be studied before and after rTMS with videomanometry

Time frame: Day 1

Secondary Outcomes

swallowing time

Swallowing function will be studied before and after rTMS with videomanometry

Time frame: Day 1

Data from ClinicalTrials.gov

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