Clinical Usefulness of Virtual Ablation Guided Catheter Ablation of Atrial Fibrillation: Prospective Randomized Study

Yonsei University40 enrolled

Overview

Radiofrequency catheter ablation is highly effective in the treatment of patients with persistent atrial fibrillation. In order to decrease the recurrence rate after catheter ablation, the investigators propose to apply 'virtual' ablation on patient-specific atria by simulating 3D atrial computer model. The investigators will test with five different set of ablation methods and find successful methods for a specific patient. Then, this result will be compared to empirical catheter ablation result by randomly controlled trial.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Atrial Fibrillation

Interventions

Virtual ablation in based 3D CT of patient who diagnosed AFPROCEDURE

conventional ablation based on physician's personal experiencePROCEDURE

Eligibility

Sex: ALLMin age: 19 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of AF patients who performed catheter ablation of atrial fibrillation due to uncontrolled pulse rate by anti-arrhythmic drug therapy. Exclusion Criteria: * AF patients who have severe heart deformations or blood problems. * The patients who had been performed catheter ablation of atrial ablation. * The patients who missed out to recording of 3D CT, echo and electrocardiography.

Locations (1)

Severance Hospital

Seoul, South Korea

Outcomes

Primary Outcomes

change of hospitalization rate

Time frame: 1, 3, 6, 12, 18 and 24 months after catheter ablation and every 6 months thereafter.

Secondary Outcomes

occurence of cardiovascular disease

Time frame: 6 months

recurrence of AF

Time frame: 6 months

Data from ClinicalTrials.gov

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