The Effect of Phrenic Nerve Blockade on Acute and Chronic Shoulder Pain in Patients for Lobectomy and Pneumonectomy

Odense University Hospital76 enrolled

Overview

The purpose of this study was to test whether peroperative infiltration of the phrenic nerve during lung surgery would protect patients against postoperative shoulder pain.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Postoperative Pain

Interventions

Phrenic nerve block with RopivacaineDRUG

Phrenic nerve block with salineDRUG

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients planned for elective lobectomy or pneumonectomy 2. 18 years or more on the day of the operation 3. Danish skills appropriate for fulfilling preoperative questionnaires Exclusion Criteria: 1. Known contralateral paresis of the Phrenic nerve 2. Allergy to Ropivacaine or Sodium Chloride 3. Preoperative ipsilateral shoulder pain 4. Infection or eczema on the intervention site. Clinical decision 5. Dementia or similar cerebral condition that makes the subject unable to perform a NRS-score of pain. Determined by clinical evaluation 6. Pregnancy 7. Acute porphyria

Locations (1)

Departement of Anaesthesia and intensive care, Odense University Hospital

Odense, Region Syddanmark, Denmark

Outcomes

Primary Outcomes

Shoulder pain within 6 hours after the operation

Shoulder pain 6 hours after the operations. Number of patients and numeric rating scale score (0-10)

Time frame: Retrospective numerical rating scale, 6 hours after the operation

Secondary Outcomes

Number of patients with shoulder pain during the first 3 postoperative days.

Time frame: Postoperative days 0-3

NRS for shoulder pain during the first 3 postoperative days.

NRS=numerical rating scale score 0-10

Time frame: Postoperative days 0-3

Opioid use during the first 3 postoperative days

Morphine equivalents

Time frame: Postoperative day 0-3

Time spent in the recovery room

Time frame: Measured at discharge from the recovery room. Estimated to be on postoperative day 0 or 1.

Shoulder pain 3 months postoperatively

Time frame: 3 months postoperatively

NRS for shoulder pain 3 months postoperatively

NRS=numerical rating scale 0-10

Time frame: 3 months postoperatively

Thoracic pain 3 months postoperatively

Time frame: 3 months postoperatively

NRS for thoracic pain 3 months postoperatively

NRS=numerical rating scale 0-10

Time frame: 3 months postoperatively

Data from ClinicalTrials.gov

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