In order to confirm the proposed metabolic effect of lacidipine these follow-up study was to provide long-term data on its impact on liver function, glucose homoeostasis and lipid metabolism. Additionally, its adverse drug reactions and antihypertensive effects were to be studied.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
53
Number of patients with rare adverse drug reactions
Time frame: up to 24 months
Change in alkaline phosphatase (AP)
Time frame: up to 24 months
Change in serum glutamic - pyruvic transaminase (SGPT)
Time frame: up to 24 months
Change in serum glutamic - oxaloacetic transaminase (SGOT)
Time frame: up to 24 months
Number of patients with abnormal changes in laboratory parameters
Time frame: up to 24 months
Changes in systolic and diastolic blood pressure
Time frame: up to 24 months
Changes in gamma glutamyl transferase (gamma-GT)
Time frame: up to 24 month
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