A randomized controlled study comparing the effect of administration of 1 gm ceftriaxone in elective cesarean section 30-60 min before skin incision versus after cord clamping.
comparing the effect of administration of 1 gm ceftriaxone in elective cesarean section 30-60 min before skin incision versus after cord clamping.on post-cesarean section infection(wound infection as a primary outcome)
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
328
Patients undergoing elective cesarean section with Gestational age 37 weeks or more. comparing the effect of administration of 1 gm ceftriaxone in elective cesarean section 30-60 min before skin incision versus after cord clamping.on post-cesarean section infection(wound infection as a primary outcome)
Antibiotic Prophylaxis for Elective Cesarean Section
Cairo, Egypt
The primary outcome is the rate of post cesarean section surgical site infection.
postoperative assessment of SSI. Patients will be followed up at 48-72 hours postoperative, at 7th days (skin suture removal) and at 6 weeks (contraception application).all patients will be contacted by telephone and interviewed. They will be rescheduled for a clinic visit if they reported signs and symptoms of wound infection (purulent discharge or erythema \>1 cm in diameter, induration of the incision site and fever).
Time frame: administration of 1gm ceftriaxone prophylaxis for elective cs and follow up surgical site infection till 40 days
other post cesarean section maternal and neonatal infection
1. Maternal complications: other post cesarean section maternal complications, namely endometritis, pyrexia, urinary tract infection and complication of drug administration such as anaphylaxis. 2. Neonatal complications: such as neonatal sepsis
Time frame: follow up ofother post cesarean section maternal and neonatal infection till 40 days of delivery
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