Terconazole Vaginal Suppository vs Fluconazole for the Treatment of Severe Vulvovaginal Candidiasis

Inclusion Criteria: * Vulvovaginal candidiasis infection is diagnosed, the symptoms evaluated using a numerical rating system based on severity (absent=0; mild=1; moderate=2; severe=3) with a minimum VVC Composite Signs/Symptoms score of 7 * Subject completes the informed consent process * Subject agrees to take study medication when scheduled * Subject complies with all clinical trial instructions. Commits to all follow-up visits * Subject agrees to abstain from sexual intercourse from the time of randomization through the first seven days immediately following treatment Exclusion Criteria: * had any other sexually transmitted disease or gynaecological abnormality requiring treatment * had a disease known to predispose to candidiasis such as diabetes mellitus, or were receiving antibiotics or corticosteriods * had used antifungal medication in the week before entry; or * were expected to menstruate within seven days of the start of treatment * infected more than one candida species