Spleen Stiffness Measurement With FibroScan

Inclusion Criteria: * All groups * Both gender, 18-79 years old * Patient able to give written informed consent form * Patient affiliated to a social security system. * Case group * Patient with chronic liver disease due to: hepatitis C virus, hepatitis B virus or Alcoholic Liver Disease and liver stiffness ≥ 14 kPa * Patient with the following examination within 3 months of LSM and SSM: ultrasound examination, blood examination, gastroscopy examination and eventually an hepatic venous pressure gradient examination * Control groups * Patient with chronic liver disease due to: HCV, HBV or Alcoholic Liver Disease and liver stiffness \< 14 kPa * Patients without chronic liver disease (Healthy Control subgroup) Exclusion Criteria: * Patient unable or unwilling to provide written informed consent. * Consuming illness (HIV infection, malignancy). * Associated comorbidities: NASH, hemochromatosis, primary sclerosing cholangitis, primary biliary cirrhosis. * Antiviral treatment during the two months before inclusion. * Pacemaker or heart defibrillator. * Pregnancy. * Liver transplantation. * BMI\>35 kg/m2. * Serum Transaminases \> 250 IU/L. * History of / or current βblockers treatment of OV. * Presence of ascites. * Previous endoscopic treatment of OV. * Patient with acute alcoholic hepatitis and associated jaundice (generally defined by total bilirubin ≥ 50 µmol/l). * Patient with hepatocellular carcinoma (HCC). * Unable or unwilling to undergo a liver stiffness measurement, a spleen stiffness measurement, an ultrasound examination, a blood examination or a gastroscopy examination.