A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer

King Chulalongkorn Memorial Hospital44 enrolled

Overview

This descriptive cross sectional study aims to directly compare the diagnostic capability of the probed-based confocal laser endomicroscopy (pCLE) and the magnifying narrow band imaging (M-NBI) in the Lugol's voiding lesions.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Esophageal Neoplasms

Interventions

OlympusDEVICE

narrow band imaging with magnification

CellvizioDEVICE

probe-based confocal laser endomicroscopy

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age over 20 years * Having histological-confirmed diagnosis of head and neck cancer * Having no esophageal symptoms Exclusion Criteria: * Having index cancer of nasopharynx * History of esophageal surgery * Having esophageal stricture or obstruction * Having esophageal varices * Known case of esophageal cancer * Uncorrectable coagulopathy and thrombocytopenia * Pregnancy * Thyrotoxicosis * Creatinine clearance less than 30 ml/min * Allergy to iodine or fluorescein.

Outcomes

Primary Outcomes

Accuracy

Diagnostic performance of the pCLE and M-NBI in Lugol's voiding lesions size larger than 5 millimeters.

Time frame: an expected average of 2 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.