Microencapsulated Fish Oil or Conjugated Linoleic Acid in Metabolic Syndrome

Universidade Federal do Rio de Janeiro37 enrolled

Overview

Our aim was to assess the effects of a hypocaloric diet, including diet fruit jelly with microencapsulated fish oil or conjugated linoleic acid or placebo, on anthropometry, body composition, insulin resistance and lipid profile in women with metabolic syndrome and genotype Pro12Pro in the PPAR gamma 2 gene.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Insulin Resistance Oxidative Stress Lipid Profile Blood Pressure Anthropometric Measure

Interventions

microencapsulated conjugated linoleic acidDIETARY_SUPPLEMENT

The microencapsulated conjugated linoleic acid received light fruit jam with microencapsulated conjugated linoleic acid (3 g/day) during 12 weeks.

microencapsulated fish oilDIETARY_SUPPLEMENT

The microencapsulated fish oil group received light fruit jam with microencapsulated fish oil (3 g/day) during 12 weeks.

light fruit jamDIETARY_SUPPLEMENT

The placebo group received light fruit jam (15 g/day) during 12 weeks.

Eligibility

Sex: FEMALEMin age: 30 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * adults women (30-45 years old); * diagnosis of metabolic syndrome, as defined by the International Diabetes Federation; * Pro12Pro genotype in gene PPARγ2. Exclusion Criteria: Participants were excluded if they: * Were allergic to strawberries or fish * Were pregnant or lactating * Took fatty acid supplements * Had undergone bariatric surgery or were being treated nutritionally or pharmacologically for reducing BM, or had taken anti-obesity drugs during the previous three months

Locations (1)

Universidade Federal do Rio de Janeiro

Rio de Janeiro, Rio de Janeiro, Brazil