Efficacy and Safety Study of Metronidazole, Nystatin and Dexamethasone Combination Therapy in Bacterial and Fungal Vaginal Infections

Inclusion Criteria: * Post-menarche women and premenopausal women, between 18 and 50 years old; * Diagnosis of bacterial vaginosis (Amsel criteria), fungal (positive KOH test)or mixed vaginal infection; * Patients who have regular menstrual cycles (patients with regular menstrual cycles with intervals between 21 to 35 days, duration of 1 to 7 days) Exclusion Criteria: * Patients who have a known hypersensitivity to components of the formula ; * Pregnant and lactating women ; * Patients with other vaginal infections, such as infection by Trichomonas vaginalis , C. trachomatis, Neisseria gonorrhoeae , herpes or HPV. * Knowledge of positive test result for human immunodeficiency virus ; * Patients in treatment of cervical intraepithelial neoplasia or carcinoma of the cervix ; * Patients who have undergone gynecological procedures in the month prior to inclusion (such as cauterization of the cervix , cervical biopsy, high-frequency surgery) ; * Patients with other vaginal or vulvar conditions that may confound interpretation of clinical response; * Patients who received intravaginal or systemic antimicrobial or antifungal therapy 14 days before randomization ; * Patients on immunosuppressive medications (such as corticosteroids , cyclosporine , etc. ) ; * Known or suspected cancer ; * Participation in any experimental study or ingestion of any experimental drug 12 months before the start of this study.