The purpose of this study is to investigate the pharmacokinetic drug interaction between Metformin and Rosuvastatin in healthy male volunteers.
Drug-drug Interaction Following Co-administration of Metformin and Rosuvastatin in Healthy Male Volunteers
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
Metformin,1000mg, once daily
Rosuvastatin, 20 mg, once daily
Metformin, 1000mg, once daily Rosuvastatin, 20mg, once daily
Samsung Medical Center(SMC)
Seoul, Gangnam-Gu, South Korea
Cmax,ss, AUCτ
Time frame: 32h
Tmax,ss
Time frame: 32h
t1/2
Time frame: 32h
Cmin,ss
Time frame: 32h
CL/Fss
Time frame: 32h
Vd/Fss
Time frame: 32h
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