BIBR 277 Capsules in Hypertensive Patients With Nephropathy

Inclusion Criteria: * Condition: Either of the following criteria is satisfied in laboratory tests: * Presence of a renal parenchymal disorder such as chronic glomerulonephritis is confirmed (serum creatinine \< 3.0 mg/dL) * Presence of a renal function disorder (serum creatinine ≥ 1.5 mg/dL to \< 3.0 mg/dL) * Age: ≥ 20 years * Sex: Either male or female * Patient status: Either outpatients or inpatients. However, the patient status should remain unchanged throughout the study period * Blood pressure (BP): * \[Outpatients\] The last 2 measurements of sitting BP out of at least 3 taken during the observation period (2 - 4 weeks) should be stable and a mean of the two measurements should be ≥160 mmHg for systolic BP (SBP) and ≥95 mmHg for diastolic BP (DBP) * \[Inpatients\] The last 2 measurements of supine BP taken during the observation period (1 week) should be stable and a mean of the 2 measurements should be ≥ 150 mmHg for SBP and ≥ 90 mmHg for DBP Exclusion Criteria: * Renovascular hypertension * Undergoing haemodialysis * Severe hypertension (Diastolic BP ≥ 120 mmHg) * Severe heart failure, angina pectoris, or history of myocardial infarction * Atrioventricular conduction disturbance (degree II to III), atrial fibrillation, or serious arrhythmia * Symptoms of cerebrovascular disorder * Serious hepatic dysfunction * Uncontrolled diabetes * Peptic ulcer * History of hypersensitivity to drugs * Hyperkalaemia * Undergoing treatment with a digitalis preparation * Pregnant, breast feeding, possibly pregnant or planning to become pregnant during this study * Otherwise judged ineligible by the investigator