The purpose of this study is to determine the effects of Activamp, a product containing gynostemma pentaphyllum extract, on body weight, fat loss and metabolic markers in healthy overweight adults.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
TRIPLE
Enrollment
100
KGK Synergize Inc.
London, Ontario, Canada
Change in body weight
Time frame: Baseline to week 12
Change in calculated BMI
Time frame: baseline to week 12
Change in calculated percent body fat
Time frame: Baseline to week 12
Change in calculated body fat mass
Time frame: Baseline to week 12
Change in calculated lean body mass
Time frame: Baseline to week 12
Change in total body fat percentage
As determined by DXA scan
Time frame: Baseline to week 12
Change in total fat mass
As determined by DXA scan
Time frame: Baseline to week 12
Change in total lean mass
As determined by DXA scan
Time frame: Baseline to week 12
Change in percent android fat
As determined by DXA scan
Time frame: Baseline to week 12
Change in percent gynoid fat
As determined by DXA scan
Time frame: Baseline to week 12
Change in percent trunk and legs fat
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
As determined by DXA scan
Time frame: Baseline to week 12
Change in percent abdominal fat
As determined by DXA scan
Time frame: Baseline to week 12
Change in anthropometric measurements
Waist and Hip circumference
Time frame: Baseline to 12 weeks
Change in blood AMPK activity
Time frame: Baseline to week 12
Change in blood metabolic parameters
lipid profile, Apo A1, Apo B, FFA, insulin and glucose, HOMA-IR, HbA1c, IGF, HsCrp, TNFalpha and glycerol
Time frame: Baseline to 12 weeks
Change in blood safety parameters
CBC, electrolytes, markers of kidney and liver function
Time frame: Baseline to week 12
Changes in safety vital signs
Blood pressure, heart rate
Time frame: Baseline to week 12
Incidence of adverse events
Time frame: Baseline to week 12