Prevalence of Eosinophilic Esophagitis in Children With Celiac Disease

N/ACompletedNCT02190513

St. John Health System, Michigan56 enrolled

Overview

Celiac disease (CD) and eosinophilic esophagitis (EE) are distinct diseases of the gastrointestinal tract with specific clinico-pathological characteristics. In recent years, in the literature, several children who underwent upper gastrointestinal endoscopy for suspected CD, which was confirmed histologically, were also found to have coexistent EE. There are reports of coexistent CD and EE. We would like to see the prevalence of EE in children with CD and the prevalence of CD in children with EE in our population, and to do so would like to review medical records. Our objectives are to determine if children with celiac disease have a high prevalence of eosinophilic esophagitis.and to determine if children with eosinophilic esophagitis have increased risk of developing celiac disease.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Celiac Disease Eosinophilic Esophagitis

Eligibility

Sex: ALLMin age: 2 YearsMax age: 21 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Seen in the Pediatric Gastroenterology clinic at St. John Hospital \& Medical Center during study time frame * Age 2-21 years old * Diagnosed with CD or EE or both based on the endoscopic and histopathological findings . Exclusion Criteria: * Gastroesophageal reflux diagnosed by PH probe. * History of chemical ingestion

Outcomes

Primary Outcomes

Review of histopathology reports of esophageal biopsies to record the number of eosinophils per high power field.

Time frame: Retrospective chart review study, no contact made with patients, so no patient time is required, expected average of 2 years