Pharmacokinetic Study of Seresis® in the Skin in Healthy Young Female Volunteers

Inclusion Criteria: * Healthy female volunteers between 18 and 30 years * With skin type II or skin type III * BMI \< 25 * Non-smokers * Volunteers who have given their written informed consent according to Good Clinical Practice (GCP) and local regulations Exclusion Criteria: * Any serious disorder that may interfere with her participation to the trial and evaluation of the safety of the test drug (e.g. liver and/or renal disease, hypervitaminosis A, psychic disorder, etc.), and/or treatment with chronic medication * Pre-treatment (less than 2 weeks prior to inclusion in this trial) and/or concomitant treatment with any drug that may influence the trial symptomatology and may interfere with evaluation of the safety of the test drug (e.g. vitamins and minerals supplementation) * Relevant allergy or known hypersensitivity to the investigational drug or its excipients * High performance sports * Alcohol and drug abuse according to Diagnostic and Statistics Manual, Version IV (DSM-IV) * Female volunteers in child-bearing age not using adequate means of birth control (contraceptive pills, Intrauterine devices (IUDs), sterilisation) * Pregnancy and/or lactation * Known abnormal values of the lab tests (if detected after enrolment, subjects will continue the treatment provided there are no medical objections) * Abnormal values of low density lipoproteins (LDL) and triglycerides (TGL) levels in blood * Participation in another clinical trial within the last 4 weeks and concurrent participation in another clinical trial * Specific dietary requirements that do not allow the volunteers to meet the dietary guidelines set out for this study