Apoptosis May Have a Role in Etiopathogenesis of Obstetric Cholestasis.

N/AUnknownNCT02192177

Zekai Tahir Burak Women's Health Research and Education Hospital50 enrolled

Overview

Intrahepatic cholestasis of pregnancy is a disease specific to pregnancy period; especially late second and third trimester. We aimed to investigate the role of apoptosis in etiopathogenesis of obstetric cholestasis.

M30 (caspases cleaved Cytokeratin-18 (CK-18) fragment) is a specific apoptosis marker. We aimed to use it to evaluate the apoptotic process.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pregnancy

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Late second or third trimester of pregnancy. Exclusion Criteria: * Foreknown systemic diseases, multiple pregnancy, smoking cigarettes.

Locations (1)

Zekai Tahir Burak Maternity Teaching Hospital

Ankara, Ankara, Turkey (Türkiye)

RECRUITING

Outcomes

Primary Outcomes

M30 value as Unit per Liter.

Time frame: Four months.

Secondary Outcomes

Percentage of delivery with cesarean section.

Time frame: Four months.

Central Contacts

Ali O Ersoy

CONTACT

+905056579157 draliersoy@yahoo.com

Data from ClinicalTrials.gov

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