Investigating a Model for Acute Ischemic Pain in Humans

N/ACompletedNCT02192242

Ludwig-Maximilians - University of Munich11 enrolled

Overview

The pathophysiology of acute ischemic pain is not well established. The aim of the present study was to investigate acute ischemic pain in humans with a view to establish a scientific model to perform future studies. The investigators examined whether peripheral nerve damage and acute inflammation occur during short episodes of acute ischemia.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Peripheral Arterial Disease

Interventions

acute ischemic painOTHER

acute ischemic pain was induced by treadmill exercise

Eligibility

Sex: ALLMin age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients over 40 years * unilateral femoral-popliteal PAD, Fontaine grade II Exclusion Criteria: * patients with pain at rest or other pain origin * diabetic polyneuropathy * deep vein thrombosis

Locations (1)

University Hospital Munich, Pettenkoferstr. 8a

Munich, Germany

Outcomes

Primary Outcomes

Induce acute ischemic pain

To induce acute ischemic pain, patients performed treadmill exercise until intolerable pain developed.

Time frame: during treadmill exercise (less than 15 minutes)

Data from ClinicalTrials.gov

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