Phase I/II Study of KP-100IT in Acute Spinal Cord Injury

Inclusion Criteria: * Age equal to or greater than 18 years and equal to or less than 75 years * Cervical spinal cord injury, and Grade A, B1 or B2 in the modified Frankel Scale at 72 hours since the injury * Subjects able to provide written informed concent, which may require a relative to sign if arm/hand function of the subject is compromised Exclusion Criteria: * Spinal cord injury at C1-C2 0r C2-C3 level * Patients not to able to start rehabilitation within a week by setup of respirator or other reason * First dose of the study drug will not be given within 78 hours since the injury * History of spinal cord injury or abnormality in spinal cavity. Or current considerable meningeal damage * Outcome assessment will not be conducted adequately through damage on injuries other than the injury * High-dose steroid therapy within 30 days before the entry * Patients who have diseases such as serious liver disorder, renal disorder, hear disease, blood dyscrasia, metabolism disorder and infections * History of malignant tumor * Patients who participated in other clinical study within 30 days before the entry * Patients who have allergies to drug scheduled to be used in the study * Administration of the study drug to the area of spinal cord injury is not appropriate for example by intrathecal infections or intrathecal tumor * Patients not able to understand "informed consent" properly * Patients who are nursing or may be pregnant * Investigator considers that the patient is not appropriate for participating in the study