Parathyroid Reimplantation in Forearm Subcutaneous Tissue During Thyroidectomy: a Simple Way to Avoid Ipoparathyroidism and Evaluate Graft Function

N/ACompletedNCT02194920

University of Roma La Sapienza20 enrolled

Overview

The purpose of this study is to evaluate safety and effectiveness of normal parathyroid tissue reimplantation in forearm subcutaneous tissue in case of accidental removal of parathyroid gland during thyroid surgery.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Thyroid Goiter Thyroid Carcinoma Multinodular Goiter Graves Diseases

Interventions

Thyroidectomy and parathyroid reimplantation in forearm subcutaneous tissuePROCEDURE

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Patients affected by benign thyroid disease undergoing thyroidectomy

Locations (1)

General Surgery Unit, ICOT Hospital

Latina, Italy

Outcomes

Primary Outcomes

Assessment of parathyroid tissue graft function by selective (left or right) parathormone measurement by vein blood sample

The primary outcome will be the assessment of reimplanted parathyroid function, evaluated by intact Parathormone (iPTH) measurement by separate blood samples (left and right arm) at 7 days, 1 month and 3 months after surgery. Ratio of 1.5 between the iPTH levels in the arm receiving graft and the opposite arm will be predictive of graft functionality

Time frame: up to 3 months

Data from ClinicalTrials.gov

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