Myocardial infarction is related with endothelial function, arterial stiffness and autonomic nervous system dysfunction, but also with arterial hypertension. Hypertension by itself is also related with endothelial function, arterial stiffness and autonomic nervous system dysfunction. Primary aim of study is to investigate how complex cardiac rehabilitation influence endothelial function, arterial stiffness and autonomic nervous system activity according to presence or absence arterial hypertension. Secondary aim is to obtain correlation between methods for the assessment of particular disorders and intercorrelation between different disorders for example endothelial function and autonomic nervous system activity.
We expect that in study groups PWV will improve better that in control group. 5% of the limit value of p \<0.05. We expect that in study groups AASI will improve better that in control group. 5% of the limit value of p \<0.05. We expect that in study groups AI will improve better that in control group. 5% of the limit value of p \<0.05. We expect that time and frequency parameters of HRV will increase in study group. 5% of the limit value of p \<0.05. We expect that parameters of HRT will improve in study group. 5% of the limit value of p \<0.05. We expect improvement in RHI in study group. 5% of the limit value of p \<0.05.
Study Type
OBSERVATIONAL
Enrollment
120
Standard program of comprehensive cardiac rehabilitation CR with physical activity, behavioral intervention, risk factor modification and intervention.
Departament of Cardiology
Lodz, Łódź Voivodeship, Poland
Arterial stiffness - Pulse wave velocity (PWV)
Arterial stiffness will be obtained by measuring carotid-femoral pulse wave velocity using Complior device.
Time frame: 24 month
Arterial stiffness - Ambulatory arterial stiffness index (AASI)
AASI index will be calculated by non-commercial software using data from ambulatory blood pressure monitoring.
Time frame: 24 month
Arterial stiffness - Augmentation index (AI)
AI will be calculated by EndoPAT2000 system.
Time frame: 24 month
Heart rate variability (HRV)
HRV parameters in time and frequency domain will be calculated by software Cardioscan 12.
Time frame: 24 month
Heart rate turbulence (HRT)
HRT parameters will be calculated by Cardioscan 10 software.
Time frame: 24 month
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