NeoVas Bioresorbable Coronary Scaffold First-in-Man Study

Inclusion Criteria: * Age must be between 18 and 75 years, men or unpregnant women * Patient must have evidence of myocardial ischemia (e.g., stable angina, unstable angina) * Total number of target lesion =1 per patient * Target lesion must be ≤ 20mm in length (visual estimation) and 2.75 to 3.75 mm in diameter（Online QCA） * Target lesion is with a visually estimated stenosis of ≥ 70% (or ≥50% and evidence of myocardial ischemia) with a TIMI flow of ≥ 1 * The target lesion can be covered by one scaffold * Patient must be an acceptable candidate for coronary artery bypass graft. * Patient is able to verbally confirm understanding of risks, benefits and treatment of receiving the NeoVas bioresorbable coronary scaffold and he/she or his/her legally authorized representative provides written informed consent prior to any clinical investigation related procedure, as approved by the appropriate Ethics Committee of the respective clinical site. Exclusion Criteria: * Patients has had a known diagnosis of acute myocardial infarction (AMI) within 30 days preceding the procedure; CK and CK-MB have not returned within normal limits at the time of procedure * Chronic total occlusion lesions(TIMI 0 grade blood flow prior to implantation), left trunk vessel lesion, ostial lesion ,multi-branch lesions needing treated, fork and bridge vessel lesions of branch vessels whose diameter ≥2.0mm(branch opening stenosis exceeds 40% or need balloon expansion); there is thrombus visible in the target blood vessels. * Severe calcified lesions and twisted lesions which cannot be pre-expanded, and lesions unsuitable for delivering and expanding stents * In-stent restenosis lesion * Patient has undergone previous stenting anywhere within the target vessel(s) within the previous 12 months, or will require stenting within the target vessel(s) within 6 months after the study procedure; target vessels that has been planted stents over a year. * Severe heart failure(over NYHA III grade ), or left ventricular ejection fraction(LVEF)\< 40%( supersonic inspection or left ventricular radiography ) * Known renal insufficiency (e.g., eGFR \<60 ml/min, or subject on dialysis) * Patients with hemorrhage tendency, an active digestive ulcer history, a cerebral hemorrhage or subarachnoid hemorrhage history, or cerebral apoplexy within half a year, and these patients who contraindicate against platelet inhibitors and anticoagulant therefore can not bear anticoagulation treatment * Patient has a known hypersensitivity or contraindication to aspirin, clopidogrel, heparin, contrast agent, polylactic acid or sirolimus that cannot be adequately pre-medicated * Life expectancy \< 12 months * Patient is participating in another device or drug study that has not reached the primary endpoint of the study. * Patient's inability to fully cooperate with the study protocol which in the investigator's opinion may limit his/her ability to participate in the study * Patient has a heart transplant. * Patient has current unstable arrhythmias, such as high risk ventricular premature beat and ventricular tachycardia. * Patient is receiving or scheduled to receive chemotherapy for malignancy within 30 days prior to or after the procedure * Patient is receiving immunosuppression therapy and has known immunosuppressive or autoimmune disease * Patient is receiving or scheduled to receive chronic anticoagulation therapy (e.g., heparin, coumadin) * Elective surgery is planned within the first 6 months after the procedure that will require discontinuing either aspirin or clopidogrel * Platelet count \<100,000 cells/mm3 or \>700,000 cells/mm3, a WBC of \<3,000 cells/mm3, or documented or suspected liver disease (including laboratory evidence of hepatitis) * Patient has extensive peripheral vascular disease that precludes safe 6 French sheath insertion