This study aims to determine the safety and effectiveness of oral melatonin as natural inducer of sleep to acquire useful EEGs in South African children following its introduction as the main agent used in the Neurophysiology department at Red Cross Children's Hospital. This is an observational retrospective study.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
194
Red Cross War Memorial Children's Hospital
Cape Town, Western Cape, South Africa
Efficacy of melatonin to induce sleep for EEG studies
Successful attainment of EEG (in comparison to the unit's previous success rate)(Definition: "successful attainment of EEG" = completed sleep EEG, without excessive artefact enabling an comprehensive report to be generated in a child who undergoes the procedure without evidence of adverse drug reactions)
Time frame: 6 months
Breakdown data from the successful EEGs -
Yield in terms of EEG abnormalities - number of abnormal studies, number of studies yielding outcomes which will alter patient management
Time frame: 6 months
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