Inferior Vena Cava Collapsibility Index in Severe Sepsis

Overview

There is debate regarding the use of non invasive (ultrasound assessed) parameters of fluid volume status in patients with sepsis. To establish the role of inferior vena cava ultrasound in guiding fluid resuscitation we first need to define the inferior vena cava collapsibility index in this population of patients. The research question is: In adult patients with sepsis, severe sepsis and septic shock what is the mean baseline inferior vena cava collapsibility index (IVCCI) prior to fluid resuscitation.

The study is an interventional cohort study using a convenience sample of adult patients in a university teaching hospital Emergency Department. Eligible participants who consent to partake in the trial will have an ultrasound assessment of their inferior vena cava performed and the IVCCI will be calculated at enrolment. Care will be provided in line with the published guidelines on sepsis management from the Surviving Sepsis Campaign and the College of Emergency Medicine. A sample size calculation has been performed which indicates that 112 patient with severe sepsis or septic shock will need to be enrolled.

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Central Contacts